CHEMICAL FACT SHEET
CHLOROFORM

July 2001

This fact sheet is part of a series of chemical fact sheets to address community concerns on public health and environmental issues associated with the Massachusetts Military Reservation (MMR). Terms identified in bold are defined in the glossary.

WHAT IS CHLOROFORM?

Chloroform, also called trichloromethane, is a colorless liquid with a pleasant odor and a slight, sweet taste. It dissolves easily in water. Chloroform is both a synthetic and naturally-occurring compound, although sources from humans, such as septic systems and other water treatment processes involving chlorination, are responsible for most of the chloroform in the environment. Chloroform enters the air and water from some industrial processes, leaking containers, and waste disposal. It also is a byproduct of the chlorination of drinking water, municipal and industrial wastewater, and swimming pool and spa water. Chloroform may also enter the environment via the chemical breakdown of chlorinated compounds.

HOW WAS CHLOROFORM USED AT THE MMR?

Chloroform is not known to be associated with any groundwater plumes emanating from MMR. Chloroform has been detected in groundwater samples from areas on and around the MMR as well as other areas on and off Cape Cod. Chloroform in the groundwater on Cape Cod is widespread. In fact, nationwide studies have found that nearly half of the groundwater locations sampled have detectable levels of chloroform. .

WHAT HAPPENS TO CHLOROFORM WHEN IT ENTERS THE ENVIRONMENT?

  • Rain or snow carries some of it to soil and water where it can filter through the ground and may reach drinking water supplies.
  • It breaks down very slowly in water (over many years).
  • It does not stick to soils very well and can travel through soil to groundwater.
  • It evaporates very quickly into the air.
  • It breaks down slowly in air (over many months)
  • It does not usually build up in plants and animals.

HOW MIGHT I BE EXPOSED TO CHLOROFORM?

You can be exposed to chloroform only when you come in contact with it by drinking, breathing, eating, or touching it. Examples include:

  • Breathing contaminated air..
  • Drinking contaminated water.
  • Touching contaminated water such as while swimming or bathing.

HOW MAY CHLOROFORM AFFECT MY HEALTH?

If you are not exposed to chloroform, it does not pose a risk to your health. If there is exposure to chloroform, several factors will determine whether harmful effects may occur and what the type and severity of those health effects may be. These factors include:

  • The dose (how much)
  • The duration (how long)
  • The route or pathway by which you are exposed (breathing, eating, drinking, or skin contact)
  • Other chemicals to which you are exposed
  • Various other personal factors (e.g., age, sex, family traits, lifestyle, personal health)

In scientific experiments conducted on laboratory animals, results indicated that the health effects of chloroform are similar whether it is inhaled or ingested. These effects include damage to the liver, kidneys, and the central nervous system of rats. Moderate amounts (300,000 parts per billion (ppb)) of chloroform affected reproduction, but it is unknown if these effects apply to humans.

Similar health effects are seen in people. In large amounts, chloroform may damage the human central nervous system, liver and kidneys. Breathing high levels in the air—900,000ppb—for a short time, may cause tiredness, dizziness, or headaches.

It is important to note that the levels of contaminants found on Cape Cod are significantly lower than the doses used in laboratory studies or the examples described above.

IS CHLOROFORM LIKELY TO CAUSE CANCER?

In laboratory studies, animals that were exposed to high levels of chloroform developed liver and kidney cancer. Although there is insufficient evidence that chloroform causes cancer in humans, EPA has listed chloroform as a probable human carcinogen based on evidence that it causes cancer in laboratory animals. The U.S. Department of Health and Human Services has determined that chloroform may reasonably be anticipated to be a carcinogen.

WHAT FEDERAL AND STATE STANDARDS EXIST TO PROTECT PUBLIC HEALTH AND THE ENVIRONMENT?

EPA has established a safe drinking water standard of 80 ppb for total trihalomethanes, a group of compounds including chloroform, bromoform, bromodichloromethane, and dibromochloromethane. This means that the total sum of all trihalomethanes in a sample should not exceed 80 ppb for safe drinking water. Trihalomethanes are a common byproduct of the chlorination of public water supplies.

According to the EPA, the risks of cancer, if any, from low level exposures to chloroform in drinking water as a result of chlorination are far outweighed by the benefits of chlorination in terms of the greatly decreased incidence of waterborne disease.

Massachusetts has established a surface water quality standard for chloroform of 470 ppb for the protection of people who may consume fish from contaminated surface waters. In addition, the Commonwealth has established guidelines of 0.01 ppb as an annual average concentration for ambient air levels of chloroform to protect public health.

HOW CAN I HAVE MY WATER OR AIR CHECKED FOR CHLOROFORM?

Your local board of health can help you determine whether you are exposed to chloroform exceeding regulatory standards. There is generally a fee associated with laboratory analysis..

WHERE CAN I GET MORE INFORMATION ABOUT THIS CHEMICAL?

For additional technical information and a review of current research, contact EPA's Safe Drinking Water Hotline at (800) 426-4791, the Massachusetts Office of Research and Standards at (617) 556-1160 or see the Agency for Toxic Substances and Disease Registry's (ATSDR) Toxicological Profile for Chloroform. Information about obtaining this profile is available by calling ATSDR's 24-hour Toxicology Information Service at (404) 639-6000 or by leaving a message on (800) 447-1544. To order toxic-ological profiles contact the National Technical Information Service at (800) 553-6847 or (707) 487-4650. There may be a fee for the profile.

GLOSSARY

parts per billion (ppb): a measure of concentration. One part per billion equals 1 part in 1,000,000,000 parts. An analogy for parts per billion is one drop in 22,000 gallons.

POINTS OF CONTACT

Joint Program Office
Bruce Ruscio
(508) 968-5824
ATSDR
Louise House
(508) 968-4362
EPA Office of Site Remediation and Restoration
Sarah Levinson
(617) 573-9614
MassDEP Office of Research and Standards
Paul Locke
(617) 556-1160
Massachusetts DPH
Catherine Zone
(508) 968-4364
Barnstable County Health Department
(508) 362-2511
Bourne Board of Health
(508) 759-0630
Bourne Water District
(508) 563-2294
Falmouth Board of Health
(508) 548-7611
Falmouth Water Department
(508) 548-7611
Mashpee Board of Health
(508) 539-1400 x555
Mashpee Water District
(508) 477-6767
Sandwich Board of Health
(508) 888-0018
Sandwich Water District
(508) 888-2775

FOR ADDITIONAL INFORMATION

Additional information about the cleanup program at the MMR is available on the program's website (http://www.mmr.org). The website includes a variety of information, including technical documents, meetings agendas and summaries, maps, glossaries, weekly reports, and news releases. It also includes links to other websites, including those of EPA Region 1, DEP, DPH, and ATSDR.

In addition, five local libraries house information repositories for the cleanup program. The libraries are:

Falmouth Public Library
123 Katherine Lee Bates Rd
Falmouth, MA 02540
(508) 457-2555
Mashpee Public Library
Steeple Street
Mashpee Commons
Mashpee, MA 02649
(508) 539-1436
Sandwich Public Library
142 Main Street
Sandwich, MA 02563
(508) 888-0625
Jonathan Bourne Library
19 Sandwich Road
Bourne, MA 02532
(508) 759-0644
US Coast Guard Library
Building 5205, Ent Street
Otis ANGB, MA 02542
(508) 968-6456

The Administrative Record, which is a public record of all documents used in decision-making, is available for review at the Falmouth Public Library or by contacting the IRP Office at (508) 968-4678.

This fact sheet was developed through a collaborative effort of the Air Force Center for Environmental Excellence (AFCEE), U.S. Environmental Protection Agency (EPA), U.S. Agency for Toxic Substances and Disease Registry (ATSDR), Massachusetts Department of Environmental Protection (DEP), Massachusetts Department of Public Health (DPH), Joint Program Office (JPO), and local officials.